202 research outputs found
Improved Implementation of Point Location in General Two-Dimensional Subdivisions
We present a major revamp of the point-location data structure for general
two-dimensional subdivisions via randomized incremental construction,
implemented in CGAL, the Computational Geometry Algorithms Library. We can now
guarantee that the constructed directed acyclic graph G is of linear size and
provides logarithmic query time. Via the construction of the Voronoi diagram
for a given point set S of size n, this also enables nearest-neighbor queries
in guaranteed O(log n) time. Another major innovation is the support of general
unbounded subdivisions as well as subdivisions of two-dimensional parametric
surfaces such as spheres, tori, cylinders. The implementation is exact,
complete, and general, i.e., it can also handle non-linear subdivisions. Like
the previous version, the data structure supports modifications of the
subdivision, such as insertions and deletions of edges, after the initial
preprocessing. A major challenge is to retain the expected O(n log n)
preprocessing time while providing the above (deterministic) space and
query-time guarantees. We describe an efficient preprocessing algorithm, which
explicitly verifies the length L of the longest query path in O(n log n) time.
However, instead of using L, our implementation is based on the depth D of G.
Although we prove that the worst case ratio of D and L is Theta(n/log n), we
conjecture, based on our experimental results, that this solution achieves
expected O(n log n) preprocessing time.Comment: 21 page
Spanning trees crossing few barriers
We consider the problem of finding low-cost spanning trees for sets of n points in the plane,
where the cost of a spanning tree is defined as the total number of intersections of tree edges
with a given set of m barriers. We obtain the following results:
(i) if the barriers are possibly intersecting line segments, then there is always a spanning
tree of cost O(min(m2,m SQRT(n)));
(ii) if the barriers are disjoint line segments, then there is always a spanning tree of cost
O(m);
(iii) if the barriers are disjoint convex objects, then there is always a spanning tree of cost
O(n + m).
All our bounds are worst-case optimal
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes. It provides detailed all-atom contact analysis of any steric problems within the molecules as well as updated dihedral-angle diagnostics, and it can calculate and display the H-bond and van der Waals contacts in the interfaces between components. An integral step in the process is the addition and full optimization of all hydrogen atoms, both polar and nonpolar. New analysis functions have been added for RNA, for interfaces, and for NMR ensembles. Additionally, both the web site and major component programs have been rewritten to improve speed, convenience, clarity and integration with other resources. MolProbity results are reported in multiple forms: as overall numeric scores, as lists or charts of local problems, as downloadable PDB and graphics files, and most notably as informative, manipulable 3D kinemage graphics shown online in the KiNG viewer. This service is available free to all users at http://molprobity.biochem.duke.edu
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